Fatal Mycoplasma Pneumoniae Infection: Case Report and Review of the Literature [Abstract]

April 25, 2012

[N A J Med Sci. 2012;5(2):126-130.] PDF File

Max Xiangtian Kong, MD; Kia Newman, MD; Ronald Goldenberg, MD;

Philip M. Tierno, Jr, PhD; Irina Mikolaenko, MD; Amy Rapkiewicz, MD*

Mycoplasma pneumoniae (M. pneumoniae) infection  is rarely fatal in young adults. Most patients have no symptoms or mild nonspecific symptoms  or signs with infection. Up to 3-10% infected people may develop pneumonia. We herein report  a fatal case of M. pneumoniae infection presenting with acute respiratory failure and brain  death in a 27 year old female. Autopsy revealed that diffuse alveolar damage in the lungs  and acute hemorrhagic leukoencephalopathy (AHLE), a hyperacute form of acute disseminated  encephalomyelitis (ADEM) in the brain. 

Key Words: Mycoplasma pneumoniae,  diffuse alveolar damage, acute hemorrhagic leukoencephalopathy Mycoplasma pneumoniae,  diffuse alveolar damage, acute hemorrhagic leukoencephalopathy 

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Max Xiangtian Kong, MD;1 Kia Newman, MD;1 Ronald Goldenberg, MD;2 Philip M. Tierno, Jr, PhD;1 Irina Mikolaenko, MD;1 Amy Rapkiewicz, MD1*

1 Department of Pathology, New York University Langone Medical Center, New York,  NY
2 Department of Medicine, New York University Langone Medical Center, New York, NY 

*Corresponding Author: NYUMC/Bellevue  Hospital, 462 First Avenue 4W39, New York, NY 10016. Tel: 212-562-3421. (Email: Dramyrap@gmail.com) 

CONFLICT OF INTEREST 

The authors have no conflict of interest to disclose. 

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